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Dose adjustment is required when taking Sildenafil (Viagra) in combination with other drugs to avoid potential interactions with nitrates and certain other drugs, which may lead to significant side effects or risks.

Sildenafil may also interact with the following other drugs and may reduce its effectiveness:

  • Alpha blockers such as alfuzosin (Uroxatral), daloxetine (Doxazosin), prazosin (Minipress), sildenafil (Viagra), tadalafil (Cialis), and vardenafil (Levitra)

When taking Dose adjustment therapy, a doctor may recommend starting therapy with one of these medications or an alternative drug to adjust the dosage in conjunction with a nitrate or alpha blocker. It is important to note that the use of alpha blockers may decrease the effectiveness of the drugs. It is also important to be aware of the potential risks of nitrates and certain other medications, as well as the interactions with certain other drugs, such as alpha blockers.

Before starting Dose adjustment therapy, discuss your medical history with your doctor to determine if you are at a high risk of developing these conditions. If you experience chest pain, shortness of breath, or nausea, or both, immediately stop the medication and inform your doctor of any symptoms or medical history.

Inform your doctor if you have kidney disease, a history of vision loss, liver disease, heart disease, or if you are taking other medications that may interact with Dose adjustment therapy.

If you are taking medications to treat chest pain or other conditions, discuss with your doctor whether any other medications or alpha blockers are suitable for you, as these may affect the effects of the medication.

Discuss with your doctor the possible interactions of the drug with other medications, especially those that interact with Nitrates, which may cause a reduction in effectiveness of the drugs. A doctor may advise you to take Nitrates before starting Dose adjustment therapy or during the first few weeks of therapy.

If you have any questions about the dosage or administration of Dose adjustment therapy, discuss with your doctor or pharmacist the following with caution:

  • Inform your doctor about any pre-existing medical conditions or medications that may increase the risk of Dose adjustment and the following information with respect to your medical history:

If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before starting Dose adjustment therapy with respect to the potential risks of the drug. You should also discuss the potential benefits and risks of Dose adjustment therapy with your doctor, as well as with other medications or alpha blockers.

This product has been prescribed for you by your doctor.This medicine is available only with your doctor's prescription.

Your doctor will decide if Dose adjustment therapy is the appropriate treatment for you. The following information about Dose adjustment therapy is included in this article:

If you have kidney disease or a history of vision loss, you should not take Dose adjustment therapy. However, if you are taking medications to treat chest pain or other conditions, discuss with your doctor or pharmacist the possible interactions with Nitrates, which may cause a reduction in effectiveness of the drugs.

If you are taking medications to treat erectile dysfunction (ED) or pulmonary arterial hypertension (PAH), talk to your doctor before starting Dose adjustment therapy with respect to the potential risks of the drug.

Dose adjustment therapy is not recommended for children under the age of 12. In the UK, the maximum recommended dose of Dose adjustment therapy is one tablet of Sildenafil, taken by mouth. The maximum recommended dose is one tablet of Dose adjustment therapy taken by mouth.

Description

Sildenafil Citrate (100mg)

Generic Name:Sildenafil Citrate 100mg

Drug Class:Heparin

Action:Increase blood flow to the penis and treat erectile dysfunction.

Dosage:100-40mg, with the recommended dose and frequency.

Common Benefits:Sildenafil helps men achieve and maintain an erection suitable for sexual activity.

Other Benefits:Sildenafil is available in different strengths, and may be used in combination with other medications.

How to Use:Take Sildenafil Citrate as directed by your healthcare provider.

Side Effects:Common side effects may include headaches, dizziness, and nasal congestion.

Precautions:Avoid driving or operating machinery until you know how this medicine affects you.

Consult your healthcare provider:If you have any medical conditions or are taking any medications, be sure to discuss them with your healthcare provider.

Uses of Sildenafil Citrate (100mg)

Sildenafil is used to treat male sexual function problems, including erectile dysfunction (ED).

How Sildenafil Citrate (100mg)works by increasing blood flow to the penis, helping men achieve and maintain an erection. This effect is known as an erection. Sildenafil is also known as Viagra.

100-40mg

Sildenafil is available in different strengths and may be used in combination with other medications.

Sildenafil is used to treat erectile dysfunction (ED).

Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

  • The usual starting dose is 50mg, taken approximately one hour before sexual activity.
  • Dosage can be adjusted depending on individual response and tolerability.
  • Take only one tablet in 24 hours, with or without food.
  • Avoid grapefruit juice, as it can increase the risk of side effects.
  • A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

  • Headache
  • Flushing
  • Nasal congestion
  • Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

  • Taking nitrates for chest pain
  • With severe heart or liver conditions
  • Under 18 years of age
  • With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

  • Nitrates
  • Alpha-blockers
  • Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

  • Generic versions are more affordable than branded Viagra.
  • Supplied by licensed UK pharmacies such as Online Chemist.
  • Avoid counterfeit products from unregulated websites.

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Store Notice: Orders placed after 11:00 AM on Friday, 23 May 2025 will be processed on the next working day, Tuesday, 27 May 2025, due to the bank holiday weekend. Thank you for your understanding.

About Sildenafil: Sildenafil is a BPH medication available over the counter in the UK.......About Pfizer: Pfizer holds the patents for most brand and generic medications. Pfizer works with manufacturers to create new and our...

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How does the drug interact with Sildenafil Tablet:Co-administration of Sildenafil Tablet with Nitroprusside can increase the risk or severity of lower urinary tract symptoms (LUTS). This interaction may occur only with your medicine. Discuss all medications, herbal remedies, and mental health treatments you are taking before starting Sildenafil Tablet. See also warnings section.

Taking Sildenafil Tablet with Nitroprusside may increase your blood pressure.How do the drugs affect each other:Sildenafil Tablet increases blood pressureTaking Sildenafil Tablet with Nitroprusside may cause a drop in blood pressure.Taking Sildenafil Tablet with Nitroprusside may cause a decrease in blood pressure.How do the drugs interact:You should not take Sildenafil Tablet with Nitroprusside together with any other medications.

Sildenafil Tablet and nitrates can cause a dangerous drop in blood pressure. Before you start taking any nitrate drug, tell your doctor about all the medicines you are taking. Sildenafil Tablet may cause dizziness and lightheadedness, while Nitrate drug may cause headache.

Nitrate drug is not addictive. Consult your doctor or pharmacist for more details.

What is the possible side effects of Sildenafil Tablet:Sudden vision loss in two nightsYou should not take Sildenafil Tablet with any of the medicines listed below.

What are the possible side effects of Sildenafil Tablet:Sudden hearing decreaseYou should not take Sildenafil Tablet with Nitroprusside together with any other medicines.

Before you start taking any nitrate drug, tell your doctor. Tell your doctor if you have sudden vision loss in two nights while taking Sildenafil Tablet while taking Nitroprusside.